THE DEFINITIVE GUIDE TO LDN-27219 PRECLINICAL RESEARCH

One particular specifically intriguing compound is LDN-27219. Whilst most tTG inhibitors are made to bind to the protein crosslinking Energetic website, LDN-27219 rather binds into the nucleotide binding pocket with the enzyme although it's in its shut-condition conformation, and stabilizes that conformation to stop crosslinking activity.seventy ei